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Hydroxypropyl methylcellulose (HMPC)
    Time:2017-11-16 13:55:28    Hits:902
Hydroxypropyl methylcellulose (HMPC) CAS NO.: 9004-65-3
SHANDONG MEDICAL PRODUCTION LICENSE NO. F2014061
Packing specifications: 20 kg/bag   20 kg/bucket
Quality standard: CP2015, USP current edition
Main application:
The product is non-ionic cellulose ether, mainly used as filmogen and gels of thin film coating and emulgator, suspending agent and stabilizer of ointment. The concentration generally is 2%-10%. In tablet granulation, it is used as adhesive, with concentration generally of 2%-5%. Hydroxypropyl methylcellulose is widely used in oral and topical preparations, mainly used as adhesive of tablet, thin film coating material and framework material of sustained-release tablet; for low viscosity, it can be used as adhesive of wet granulation tablet and adhesive of dry granulation; and the hydroxypropyl methylcellulose with high viscosity can be used as retardant of framework of tablet and capsule, with the function of delaying drug release.
Indicator/model USP/CP2910(60EH) USP/CP2906(65EH) USP/CP2208(70EH) USP/CP1828(90EH)
Methoxy group % 28.0-30.0 27.0-30.0 19.0-24.0 16.5-20.0
Hydroxypropoxy % 7.0-12.0 4.0-7.5 4.0-12.0 23.0-32.0
Residue on ignition ≤1.5%
Heavy metal ≤0.002%
PH 5.0-8.0
Application 2910(60EH) is suitable for adhesive of wet granulation, conventional thin film coating material and closed tablet core; 2208(70EH) is applied to matrix tablet of sustained-release preparations; 2906(65EH) is often used as thickening agent.
 

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